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1

Serial killing by cytotoxic T lymphocytes: T cell receptor triggers degranulation, re-filling of the lytic granules and secretion of lytic proteins via a non-granule pathway

Sylvie Isaaz, Kristin Baetz, Kristin Olsen, Eckhard Podack, Gillian M. Griffiths

Journal:

European Journal of Immunology

Year:

1995

Language:

english

File:

PDF, 1.84 MB

english, 1995

2

CD30: an important new target in hematologic malignancies

Deutsch, Yehuda E., Tadmor, Tamar, Podack, Eckhard R., Rosenblatt, Joseph D.

Journal:

Leukemia and Lymphoma

Year:

2011

Language:

english

File:

PDF, 820 KB

english, 2011

3

Genetic immunotherapy by intrapleural, intraperitoneal and subcutaneous injection of IL-2 gene-modified Lewis lung carcinoma cells

Yuji Heike, Minako Takahashi, Tatsuo Ohira, Ichiro Naruse, Seiji Hama, Yuichiro Ohe, Takashi Kasai, Hisao Fukumoto, Kristin J. Olsen, Eckhard E. Podack, Nagahiro Saijo

Journal:

International Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 97 KB

english, 1997

4

Impaired nonrestricted cytolytic activity in systemic lupus erythematosus

William Stohl, Julie E. Elliott, Lily Li, Eckhard R. Podack, David H. Lynch, Chaim O. Jacob

Journal:

Arthritis & Rheumatism

Year:

1997

Language:

english

File:

PDF, 844 KB

english, 1997

5

SC5b-7, SC5b-8 and SC5b-9 complexes of complement: ultrastructure and localization of the S-protein (vitronectin) within the macromolecules

Klaus P. Preissner, Eckhard R. Podack, Hans J. Müller-Eberhard

Journal:

European Journal of Immunology

Year:

1989

Language:

english

File:

PDF, 2.06 MB

english, 1989

6

Detection of perforin and granzyme A mRNA in infiltrating cells during infection of mice with lymphocytic choriomeningitis virus

Christoph Müller, David Kägi, Toni Aebischer, Bernhard Odermatt, Werner Held, Eckhard R. Podack, Rolf M. Zinkernagel, Hans Hengartner

Journal:

European Journal of Immunology

Year:

1989

Language:

english

File:

PDF, 4.63 MB

english, 1989

7

Regulation of perforin gene expression in a T cell hybrid with inducible cytolytic activity

José A. García-Sanz, Eckhard R. Podack

Journal:

European Journal of Immunology

Year:

1993

Language:

english

File:

PDF, 1.16 MB

english, 1993

8

Rapid induction of tumor necrosis factor cytotoxicity in naive splenic T cells by simultaneous CD80 (B7.1) and CD54 (ICAM-1) co-stimulation

Makoto Nishio, Eckhard R. Podack

Journal:

European Journal of Immunology

Year:

1996

Language:

english

File:

PDF, 471 KB

english, 1996

9

APRIL (TNFSF13) regulates collagen-induced arthritis, IL-17 production and Th2 response

Yanping Xiao, Seiichi Motomura, Eckhard R. Podack

Journal:

European Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 445 KB

english, 2008

10

TNF superfamily member 13, APRIL, inhibits allergic lung inflammation

Yanping Xiao, Seiichi Motomura, Vadim Deyev, Eckhard R. Podack

Journal:

European Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 441 KB

english, 2011

11

The central role of CD30L/CD30 interactions in allergic rhinitis pathogenesis in mice

Takafumi Fuchiwaki, Xun Sun, Kenjiro Fujimura, Hisakata Yamada, Kensuke Shibata, Hiromi Muta, Eckhard R. Podack, Hideyuki Kawauchi, Yasunobu Yoshikai

Journal:

European Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 409 KB

english, 2011

12

Combination effect of vaccination with IL2 and IL4 cdna transfected cells on the induction of a therapeutic immune response against lewis lung carcinoma cells

Yuichiro Ohe, Eckhard R. Podack, Kristin J. Olsen, Yuki Miyahara, Tatsuo Ohira, Kaoru Miura, Kazuto Nishio, Nagahiro Saijo

Journal:

International Journal of Cancer

Year:

1993

Language:

english

File:

PDF, 619 KB

english, 1993

13

Molecular mechanisms of cytolysis by complement and by cytolytic lymphocytes

Eckhard R. Podack

Journal:

Journal of Cellular Biochemistry

Year:

1986

Language:

english

File:

PDF, 2.53 MB

english, 1986

14

The molecular mechanism of lymphocyte-mediated tumor cell lysis

Eckhard R Podack

Journal:

Immunology Today

Year:

1985

Language:

english

File:

PDF, 7.33 MB

english, 1985

15

Execution and suicide: cytotoxic lymphocytes enforce Draconian laws through separate molecular pathways

Eckhard R Podack

Journal:

Current Opinion in Immunology

Year:

1995

Language:

english

File:

PDF, 507 KB

english, 1995

16

Abundant perforin expression at the maternal–fetal interface: guarding the semiallogeneic transplant?

Daniel Rukavina, Eckhard R Podack

Journal:

Immunology Today

Year:

2000

Language:

english

File:

PDF, 147 KB

english, 2000

17

Heat Shock Fusion Protein gp96-Ig Mediates Strong CD8 CTL Expansion in vivo

NATAŠA ŠTRBO, KOICHI YAMAZAKI, KELVIN LEE, DANIEL RUKAVINA, ECKHARD R. PODACK

Journal:

American Journal of Reproductive Immunology

Year:

2002

Language:

english

File:

PDF, 173 KB

english, 2002

18

Progesterone Induced Blocking Factor (PIBF) Mediates Progesterone Induced Suppression of Decidual Lymphocyte Cytotoxicity

GORDANA LAŠKARIN, VLATKA S. TOKMADŽIĆ, NATAŠA ŠTRBO, TATJANA BOGOVIĆ, JULIA SZEKERES-BARTHO, LJILJANA RANDIĆ, ECKHARD R. PODACK, DANIEL RUKAVINA

Journal:

American Journal of Reproductive Immunology

Year:

2002

Language:

english

File:

PDF, 519 KB

english, 2002

19

IL-18 is Present at the Maternal–Fetal Interface and Enhances Cytotoxic Activity of Decidual Lymphocytes

VLATKA S. TOKMADZ̆IĆ, YOSHIYUKI TSUJI, TATJANA BOGOVIĆ, GORDANA LAŠKARIN, KRISTIJAN CUPURDIJA, NATAŠŠA Š TRBO, KOJI KOYAMA, HARUKI OKAMURA, ECKHARD R. PODACK, DAN

Journal:

American Journal of Reproductive Immunology

Year:

2002

Language:

english

File:

PDF, 642 KB

english, 2002

20

The absence of B lymphocytes reduces the number and function of T-regulatory cells and enhances the anti-tumor response in a murine tumor model

Tamar Tadmor, Yu Zhang, Hyun-Mi Cho, Eckhard R. Podack, Joseph D. Rosenblatt

Journal:

Cancer Immunology, Immunotherapy

Year:

2011

Language:

english

File:

PDF, 689 KB

english, 2011

21

How to Polymerize in Order to Survive

Eckhard R. Podack

Journal:

Year:

2009

Language:

english

File:

PDF, 248 KB

english, 2009

22

Structure, Function and Expression of Murine and Human Perforin 1 (P1)

Eckhard R. Podack, David M. Lowrey, Mathias Lichtenheld, Kristin J. Olsen, Tony Aebischer, Daniel Binder, Fabio Rupp, Hans Hengartner

Journal:

Immunological Reviews

Year:

1988

Language:

english

File:

PDF, 2.05 MB

english, 1988

23

Perforin-Expressing Lymphocytes in Peripheral Blood and Decidua of Human First-Trimester Pathological Pregnancies

Gordan Gulan, Eckhard R. Podack, Dr. Daniel Rukavina, Lea Gudelj, Gordana Rubesa, Oleg Petrovic, Peter M. Johnson, Stephen E. Christmas

Journal:

American Journal of Reproductive Immunology

Year:

1997

Language:

english

File:

PDF, 803 KB

english, 1997

24

Down-Regulated Expression of Perforin-Positive/CD16+ Cells in the Peripheral Blood Lymphocytes in the First Trimester of Pregnancy and Up-Regulation at the End of Pregnancy

Dr. Daniel Rukavina, Eckhard R. Podack, Gordana Rubesa, Suzana Spanjol-Pandelo, Ljiljana Randic

Journal:

American Journal of Reproductive Immunology

Year:

1997

Language:

english

File:

PDF, 613 KB

english, 1997

25

REVIEW ARTICLE: Secreted Heat Shock Protein gp96-Ig: An Innovative Vaccine Approach

Natasa Strbo, Eckhard R. Podack

Journal:

American Journal of Reproductive Immunology

Year:

2008

Language:

english

File:

PDF, 401 KB

english, 2008

26

CD30—Governor of Memory T Cells?

ECKHARD R. PODACK, NATASA STRBO, VLATKA SOTOSEC, HIROMI MUTA

Journal:

Annals of the New York Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 1.98 MB

english, 2002

27

Formation of transmembrane tubules by spontaneous polymerization of the hydrophilic complement protein C9

Tschopp, Jürg, Müller-Eberhard, Hans J., Podack, Eckhard R.

Journal:

Year:

1982

File:

PDF, 867 KB

1982

28

Assembly of two types of tubules with putative cytolytic function by cloned natural killer cells

Podack, Eckhard R., Dennert, Gunther

Journal:

Year:

1983

File:

PDF, 750 KB

1983

29

Structure and function of human perforin

Lichtenheld, Mathias G., Olsen, Kristin J., Lu, Ping, Lowrey, David M., Hameed, Arif, Hengartner, Hans, Podack, Eckhard R.

Journal:

Year:

1988

File:

PDF, 565 KB

1988

30

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

Kägi, David, Ledermann, Birgit, Bürki, Kurt, Seiler, Peter, Odermatt, Bernhard, Olsen, Kristin J., Podack, Eckhard R., Zinkernagel, Rolf M., Hengartner, Hans

Journal:

Year:

1994

File:

PDF, 885 KB

1994

31

Induction of CD8 T-cell-Ifn-γ response and positive clinical outcome after immunization with gene-modified allogeneic tumor cells in advanced non-small-cell lung carcinoma

Raez, Luis E, Cassileth, Peter A, Schlesselman, James J, Padmanabhan, Swaminathan, Fisher, Eva Z, Baldie, Paulette A, Sridhar, Kasi, Podack, Eckhard R

Journal:

Cancer Gene Therapy

Year:

2003

Language:

english

File:

PDF, 268 KB

english, 2003

32

Regulation of Fas-dependent activation-induced T cell apoptosis by cAMP signaling: a potential role for transcription factor NF-κB

Ivanov, Vladimir N, Lee, Richard K, Podack, Eckhard R, Malek, Thomas R

Journal:

Year:

1997

Language:

english

File:

PDF, 681 KB

english, 1997

33

Induction of a TRAIL mediated suicide program by interferon alpha in primary effusion lymphoma

Toomey, Ngoc L, Deyev, Vadim V, Wood, Charles, Boise, Lawrence H, Scott, Duncan, Liu, Lei Hua, Cabral, Lisa, Podack, Eckhard R, Barber, Glen N, Harrington Jr, William J

Journal:

Year:

2001

Language:

english

File:

PDF, 422 KB

english, 2001

34

A “Minimal Signal-Stepwise Activation” Analysis of Functional Maturation of T Lymphocytes

Fritz H. Bach, Robin L. Geller, Peter J. Nelson, Simon Panzer, Gianni Gromo, Mark R. Benfield, Luca Inverardi, Eckhard R. Podack, Jean C. Witson, J. P. Houchins, Barbara J. Alter

Journal:

Immunological Reviews

Year:

1989

Language:

english

File:

PDF, 7.02 MB

english, 1989

35

Present and future of lung cancer vaccines

Raez, Luis E, Rosenblatt, Joseph D, Podack, Eckhard R

Journal:

Expert Opinion on Emerging Drugs

Year:

2006

Language:

english

File:

PDF, 216 KB

english, 2006

36

CD30-Regulated Apoptosis in Murine CD8 T Cells after Cessation of TCR Signals

William G. Telford, Sang Yun Nam, Eckhard R. Podack, Richard A. Miller

Journal:

Cellular Immunology

Year:

1997

Language:

english

File:

PDF, 2.00 MB

english, 1997

37

Generation of Tumor-Specific Cytotoxic T Lymphocytes by Stimulation with HPV Type 16 E7 Peptide-Pulsed Dendritic Cells: An Approach to Immunotherapy of Cervical Cancer

Wolfgang M.J. Schoell, Ramin Mirhashemi, Bai Liu, Mike F. Janicek, Eckhard R. Podack, Manuel A. Penalver, Hervy E. Averette

Journal:

Gynecologic Oncology

Year:

1999

Language:

english

File:

PDF, 208 KB

english, 1999

38

Severe intrahepatic cholestasis in patients treated with recombinant interleukin-2 and lymphokine-activated killer cells

Mitchel Hoffman, Abraham Mittelman, Brad Dworkin, William Rosenthal, Deborah Beneck, Elizabeth Gafney, Zalmen Arlin, Daniel Levitt, Eckhard Podack

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

1989

Language:

english

File:

PDF, 1014 KB

english, 1989

39

In vitro and in vivo growth of B16F10 melanoma cells transfected with interleukin-4 cDNA and gene therapy with the transfectant

Tatsuo Ohira, Yuichiro Ohe, Yuji Heike, Eckhard R. Podack, Kristin J. Olsen, Kazuto Nishio, Makoto Nishio, Yuki Miyahara, Yasunori Funayama, Hayato Ogasawara, Hitoshi Arioka, Hiroshi Kunikane, Minoru

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

1994

Language:

english

File:

PDF, 572 KB

english, 1994

40

Regulation of lymphocyte clustering by CD30-mediated ICAM-1 up-regulation

Sang-Yun Nam, Kyong-Shin Cho, Young-Moon Heo, Jong-Cheon Ha, Young-Hyun Kim, Ho Keun Yi, Pyong Han Hwang, Hyung-Min Kim, Eckhard R Podack

Journal:

Cellular Immunology

Year:

2002

Language:

english

File:

PDF, 482 KB

english, 2002

41

Murine cytomegalovirus retinitis during retrovirus-induced immunodeficiency (MAIDS) in mice: interleukin-2 immunotherapy correlates with increased intraocular levels of perforin mRNA

Richard D. Dix, Eckhard R. Podack, Scott W. Cousins

Journal:

Antiviral Research

Year:

2003

Language:

english

File:

PDF, 248 KB

english, 2003

42

On the Mechanism and Control of the Malonyl-CoA-Dependent Chain Elongation of Fatty Acids : Characterization of Hexenoyl-CoA Reductase from Liver and Adrenal Cortex as a Constituent of the Microsomal Chain Elongation

Eckhard R. Podack, Max Lakomek, Gisela Saathoff, Werner Seubert

Journal:

Year:

1974

Language:

english

File:

PDF, 899 KB

english, 1974

43

On the Mechanism and Control of the Malonyl-CoA-Dependent Chain Elongation of Fatty Acids. The Malonyl-Transfer Reaction

Eckhard R. PODACK, Gisela SAATHOFF, Werner SEUBERT

Journal:

Year:

1974

Language:

english

File:

PDF, 518 KB

english, 1974

44

A Hammerhead Ribozyme That Cleaves Perforin and Fas-ligand RNAsin Vitro

Zhimei Du, Camillo Ricordi, Eckhard Podack, Ricardo L. Pastori

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 161 KB

english, 1996

45

Effector Cells Derived from Host CD8 Memory T Cells Mediate Rapid Resistance against Minor Histocompatibility Antigen-Mismatched Allogeneic Marrow Grafts without Participation of Perforin, Fas Ligand, and the Simultaneous Inhibition of 3 Tumor Necrosis Factor Family Effector Pathways

Zachary Zimmerman, Alwi Shatry, Vadim Deyev, Eckhard Podack, Michele Mammolenti, Bruce R. Blazar, Hideo Yagita, Robert B. Levy

Journal:

Biology of Blood and Marrow Transplantation

Year:

2005

Language:

english

File:

PDF, 401 KB

english, 2005

46

Tumor immunogenicity and responsiveness to cancer vaccine therapy: The state of the art

Taylor H. Schreiber, Luis Raez, Joseph D. Rosenblatt, Eckhard R. Podack

Journal:

Seminars in Immunology

Year:

2010

Language:

english

File:

PDF, 389 KB

english, 2010

47

Increased perforin expression in multiple sclerosis patients during exacerbation of disease in peripheral blood lymphocytes

Gordana Rubeša, Eckhard R Podack, Juraj Sepčić, Daniel Rukavina

Journal:

Journal of Neuroimmunology

Year:

1997

Language:

english

File:

PDF, 268 KB

english, 1997

48

Cytotoxic Cell Granule-Mediated Apoptosis: Perforin Delivers Granzyme B-Serglycin Complexes into Target Cells without Plasma Membrane Pore Formation

Sunil S Metkar, Baikun Wang, Miguel Aguilar-Santelises, Srikumar M Raja, Lars Uhlin-Hansen, Eckhard Podack, Joseph A Trapani, Christopher J Froelich

Journal:

Year:

2002

Language:

english

File:

PDF, 532 KB

english, 2002

49

Perforin Is Required for Innate and Adaptive Immunity Induced by Heat Shock Protein Gp96

Natasa Strbo, Satoshi Oizumi, Vlatka Sotosek-Tokmadzic, Eckhard R. Podack

Journal:

Year:

2003

Language:

english

File:

PDF, 416 KB

english, 2003

50

Analysis of Perforin Expression in Human Peripheral Blood Lymphocytes, CD 56+ Natural Killer Cell Subsets and Its Induction by Interleukin-2

Konjevic, Gordana, Schlesinger, Barbara, Cheng, Lirong, Olsen, Kristin J., Podack, Eckhard R., Spuzic, Ivan

Journal:

Immunological Investigations

Year:

1995

Language:

english

File:

PDF, 691 KB

english, 1995

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